G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modelling of GPCRs is - in order to understand the ligand-receptor interactions and functionality of GPCRs on molecular level - an important tool. The book "Modelling of GPCRs - a practical handbook" is focussed onto a practical introduction into molecular modelling of GPCRs. This book is very useful for beginners in GPCR modelling, but also addresses the advanced GPCR modeller: On the one hand, the book introduces principles of GPCR modelling, including extensive examples. On the other hand, detailed outlooks onto advanced GPCR modelling techniques are presented. Furthermore, the book includes important data, like information about crystal structures in a summarized manner or amino acid sequences, which are essential for GPCR modelling in general. Due to an increase in efficacy and data handling most modellers use LINUX as operating system. To address this, a summary of most important LINUX commands with examples is presented within the book.
This book gives insight to current affairs of the world from a biblical standpoint. Inspirational and thought provoking best describe the details. The challenge question for everyone is...Do you suffer from a reprobate mind? Theresa Seawood, a loving ordinary meek woman, steps forward on faith to learn God's word while tempting others to seek as well, the knowledge of God. Theresa introduces the theory that we are living in a recycling of humanity and humiliations. Take a dive and explore through this book to discover how the present days are a recycled process of the old days for those living a Godless life. Throughout the book, Theresa asks the world to identify their weaknesses, read the bible, and pray a simple request.
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